2N1T
Dynamic binding mode of a synaptotagmin-1-SNARE complex in solution
Summary for 2N1T
Entry DOI | 10.2210/pdb2n1t/pdb |
Related | 1SFC 1UOW |
NMR Information | BMRB: 6235 |
Descriptor | Vesicle-associated membrane protein 2, Syntaxin-1A, Synaptosomal-associated protein 25, ... (5 entities in total) |
Functional Keywords | synaptotagmin-1, c2b domain, syntaxin-1a, synaptobrevin-2, snap-25, snap-25a, snare complex, exocytosis |
Biological source | Rattus norvegicus (brown rat,rat,rats) More |
Cellular location | Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane; Single-pass type IV membrane protein: P63045 P32851 Cytoplasm, perinuclear region : P60880 P60880 Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane; Single-pass membrane protein: P21579 |
Total number of polymer chains | 5 |
Total formula weight | 51428.32 |
Authors | Brewer, K.,Bacaj, T.,Cavalli, A.,Camilloni, C.,Swarbrick, J.,Liu, J.,Zhou, A.,Zhou, P.,Barlow, N.,Xu, J.,Seven, A.,Prinslow, E.,Voleti, R.,Haussinger, D.,Bonvin, A.,Tomchick, D.,Vendruscolo, M.,Graham, B.,Sudhof, T.,Rizo, J. (deposition date: 2015-04-21, release date: 2015-06-03, Last modification date: 2024-05-15) |
Primary citation | Brewer, K.D.,Bacaj, T.,Cavalli, A.,Camilloni, C.,Swarbrick, J.D.,Liu, J.,Zhou, A.,Zhou, P.,Barlow, N.,Xu, J.,Seven, A.B.,Prinslow, E.A.,Voleti, R.,Haussinger, D.,Bonvin, A.M.,Tomchick, D.R.,Vendruscolo, M.,Graham, B.,Sudhof, T.C.,Rizo, J. Dynamic binding mode of a Synaptotagmin-1-SNARE complex in solution. Nat.Struct.Mol.Biol., 22:555-564, 2015 Cited by PubMed: 26030874DOI: 10.1038/nsmb.3035 PDB entries with the same primary citation |
Experimental method | SOLUTION NMR |
Structure validation
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