2N14
Mdmx-295
Summary for 2N14
| Entry DOI | 10.2210/pdb2n14/pdb |
| Related | 2N06 2N0U 2N0W |
| NMR Information | BMRB: 25546 |
| Descriptor | Protein Mdm4, 4-({(4S,5R)-4-(3-chlorophenyl)-5-(4-chlorophenyl)-2-[4-methoxy-2-(propan-2-yloxy)phenyl]-4,5-dihydro-1H-imidazol-1-yl}carbonyl)piperazin-2-one (2 entities in total) |
| Functional Keywords | mdmx, signaling protein |
| Biological source | Homo sapiens (human) |
| Cellular location | Nucleus: O15151 |
| Total number of polymer chains | 1 |
| Total formula weight | 10742.39 |
| Authors | Grace, C.R.,Kriwacki, R.W. (deposition date: 2015-03-20, release date: 2016-01-27, Last modification date: 2016-05-04) |
| Primary citation | Grace, C.R.,Ban, D.,Min, J.,Mayasundari, A.,Min, L.,Finch, K.E.,Griffiths, L.,Bharatham, N.,Bashford, D.,Kiplin Guy, R.,Dyer, M.A.,Kriwacki, R.W. Monitoring Ligand-Induced Protein Ordering in Drug Discovery. J.Mol.Biol., 428:1290-1303, 2016 Cited by PubMed: 26812210DOI: 10.1016/j.jmb.2016.01.016 PDB entries with the same primary citation |
| Experimental method | SOLUTION NMR |
Structure validation
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