2N02

Solution structure of the A147T variant of the mitochondrial translocator protein (tspo) in complex with pk11195

Summary for 2N02

• Entry DOI: 10.2210/pdb2n02/pdb
• Related: 2mgy
• NMR Information: BMRB: 25513
• Descriptor: Translocator protein, N-[(2R)-butan-2-yl]-1-(2-chlorophenyl)-N-methylisoquinoline-3-carboxamide (2 entities in total)
• Functional Keywords: membrane protein, translocator protein (tspo), protein-ligand complex, mitochondria, pk11195, peripheral benzodiazepine receptor, a147t
• Biological source: Mus musculus (mouse)
• Total number of polymer chains: 1
• Total formula weight: 19181.57

Authors

Jaremko, M.,Jaremko, L.,Giller, K.,Becker, S.,Zweckstetter, M. (deposition date: 2015-03-04, release date: 2015-06-10, Last modification date: 2023-06-14)

• Primary citation: Jaremko, M.,Jaremko, M.,Giller, K.,Becker, S.,Zweckstetter, M.; Structural Integrity of the A147T Polymorph of Mammalian TSPO.; Chembiochem, 16:1483-1489, 2015; PubMed: 25974690; DOI: 10.1002/cbic.201500217

Experimental method

SOLUTION NMR