2MWN

Talin-F3 / RIAM N-terminal Peptide complex

2MWN の概要

• エントリーDOI: 10.2210/pdb2mwn/pdb
• NMR情報: BMRB: 25343
• 分子名称: Amyloid beta A4 precursor protein-binding family B member 1-interacting protein, Talin-1 (2 entities in total)
• 機能のキーワード: riam, talin, integrin, structural protein-signaling protein complex, structural protein/signaling protein
• 由来する生物種: Homo sapiens (human); 詳細
• 細胞内の位置: Cell membrane ; Peripheral membrane protein : Q7Z5R6; Cell projection, ruffle membrane ; Peripheral membrane protein ; Cytoplasmic side : Q9Y490
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 13339.30

構造登録者

Yang, J.,Zhu, L.,Zhang, H.,Hirbawi, J.,Fukuda, K.,Dwivedi, P.,Liu, J.,Byzova, T.,Plow, E.F.,Wu, J.,Qin, J. (登録日: 2014-11-13, 公開日: 2014-12-17, 最終更新日: 2023-06-14)

• 主引用文献: Yang, J.,Zhu, L.,Zhang, H.,Hirbawi, J.,Fukuda, K.,Dwivedi, P.,Liu, J.,Byzova, T.,Plow, E.F.,Wu, J.,Qin, J.; Conformational activation of talin by RIAM triggers integrin-mediated cell adhesion.; Nat Commun, 5:5880-5880, 2014; PubMed: 25520155; DOI: 10.1038/ncomms6880

実験手法

SOLUTION NMR