2MW3

Solution NMR structure of the lasso peptide streptomonomicin

Summary for 2MW3

• Entry DOI: 10.2210/pdb2mw3/pdb
• NMR Information: BMRB: 25297
• Descriptor: Lasso peptide (1 entity in total)
• Functional Keywords: lasso peptide, antibiotic, macrocycle, ripp, unknown function
• Biological source: Streptomonospora alba
• Total number of polymer chains: 1
• Total formula weight: 2252.56

Authors

Tietz, J.I.,Zhu, L.,Mitchell, D.A.,Metelev, M.,Melby, J.O.,Blair, P.M.,Livnat, I.,Severinov, K. (deposition date: 2014-10-24, release date: 2015-01-28, Last modification date: 2023-06-14)

• Primary citation: Metelev, M.,Tietz, J.I.,Melby, J.O.,Blair, P.M.,Zhu, L.,Livnat, I.,Severinov, K.,Mitchell, D.A.; Structure, bioactivity, and resistance mechanism of streptomonomicin, an unusual lasso Peptide from an understudied halophilic actinomycete.; Chem.Biol., 22:241-250, 2015; PubMed: 25601074; DOI: 10.1016/j.chembiol.2014.11.017

Experimental method

SOLUTION NMR