2MTP
The structure of Filamin repeat 21 bound to integrin
Summary for 2MTP
Entry DOI | 10.2210/pdb2mtp/pdb |
NMR Information | BMRB: 25176 |
Descriptor | Filamin-A, Integrin alpha-IIb, Integrin beta-3 (3 entities in total) |
Functional Keywords | integrin, filamin, protein binding-cell adhesion complex, protein binding/cell adhesion |
Biological source | Homo sapiens (human) More |
Cellular location | Cytoplasm, cell cortex: P21333 Membrane; Single-pass type I membrane protein: P08514 Cell membrane ; Single- pass type I membrane protein : P05106 |
Total number of polymer chains | 3 |
Total formula weight | 17962.83 |
Authors | |
Primary citation | Liu, J.,Das, M.,Yang, J.,Ithychanda, S.S.,Yakubenko, V.P.,Plow, E.F.,Qin, J. Structural mechanism of integrin inactivation by filamin. Nat.Struct.Mol.Biol., 22:383-389, 2015 Cited by PubMed: 25849143DOI: 10.1038/nsmb.2999 PDB entries with the same primary citation |
Experimental method | SOLUTION NMR |
Structure validation
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