2MPQ
Solution structure of the sodium channel toxin Hd1a
Summary for 2MPQ
Entry DOI | 10.2210/pdb2mpq/pdb |
NMR Information | BMRB: 19998 |
Descriptor | Hd1a (1 entity in total) |
Functional Keywords | spider toxin, disulfide-rich peptide, sodium channel, knottin, inhibitor cystine knot, toxin |
Biological source | Haplopelma doriae |
Total number of polymer chains | 1 |
Total formula weight | 3891.48 |
Authors | Klint, J.K.,Mobli, M.,King, G.F. (deposition date: 2014-06-01, release date: 2015-03-25, Last modification date: 2023-06-14) |
Primary citation | Klint, J.K.,Smith, J.J.,Vetter, I.,Rupasinghe, D.B.,Er, S.Y.,Senff, S.,Herzig, V.,Mobli, M.,Lewis, R.J.,Bosmans, F.,King, G.F. Seven novel modulators of the analgesic target NaV 1.7 uncovered using a high-throughput venom-based discovery approach. Br.J.Pharmacol., 172:2445-2458, 2015 Cited by PubMed: 25754331DOI: 10.1111/bph.13081 PDB entries with the same primary citation |
Experimental method | SOLUTION NMR |
Structure validation
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