2MPM

Structural Basis of Receptor Sulfotyrosine Recognition by a CC Chemokine: the N-terminal Region of CCR3 Bound to CCL11/Eotaxin-1

Summary for 2MPM

• Entry DOI: 10.2210/pdb2mpm/pdb
• Related: 1EOT 2EOT
• NMR Information: BMRB: 19989
• Descriptor: Eotaxin, CCR3 (2 entities in total)
• Functional Keywords: chemokine ccl11, chemokine receptor ccr3, sulfopeptide, cytokine
• Biological source: Homo sapiens (human); More
• Cellular location: Secreted: P51671
• Total number of polymer chains: 2
• Total formula weight: 10320.96

Authors

Millard, C.J.,Ludeman, J.P.,Canals, M.,Bridgford, J.L.,Hinds, M.G.,Clayton, D.J.,Christopoulos, A.,Payne, R.J.,Stone, M.J. (deposition date: 2014-05-26, release date: 2014-12-10)

• Primary citation: Millard, C.J.,Ludeman, J.P.,Canals, M.,Bridgford, J.L.,Hinds, M.G.,Clayton, D.J.,Christopoulos, A.,Payne, R.J.,Stone, M.J.; Structural Basis of Receptor Sulfotyrosine Recognition by a CC Chemokine: The N-Terminal Region of CCR3 Bound to CCL11/Eotaxin-1.; Structure, 22:1571-1581, 2014; PubMed: 25450766; DOI: 10.1016/j.str.2014.08.023

Experimental method

SOLUTION NMR