2MLI
NMR structure of B25-(alpha, beta)-dehydro-phenylalanine insulin
Summary for 2MLI
Entry DOI | 10.2210/pdb2mli/pdb |
NMR Information | BMRB: 19822 |
Descriptor | Insulin (2 entities in total) |
Functional Keywords | insulin analog, hormone |
Biological source | Homo sapiens (human) More |
Cellular location | Secreted: P01308 P01308 |
Total number of polymer chains | 2 |
Total formula weight | 5792.58 |
Authors | |
Primary citation | Menting, J.G.,Yang, Y.,Chan, S.J.,Phillips, N.B.,Smith, B.J.,Whittaker, J.,Wickramasinghe, N.P.,Whittaker, L.J.,Pandyarajan, V.,Wan, Z.L.,Yadav, S.P.,Carroll, J.M.,Strokes, N.,Roberts, C.T.,Ismail-Beigi, F.,Milewski, W.,Steiner, D.F.,Chauhan, V.S.,Ward, C.W.,Weiss, M.A.,Lawrence, M.C. Protective hinge in insulin opens to enable its receptor engagement. Proc.Natl.Acad.Sci.USA, 111:E3395-E3404, 2014 Cited by PubMed: 25092300DOI: 10.1073/pnas.1412897111 PDB entries with the same primary citation |
Experimental method | SOLUTION NMR |
Structure validation
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