2MKB

Structure of NS2(113-137) GBVB protein

2MKB の概要

• エントリーDOI: 10.2210/pdb2mkb/pdb
• 関連するPDBエントリー: 2lzp 2lzq
• NMR情報: BMRB: 19765
• 分子名称: Protease NS2-3 (1 entity in total)
• 機能のキーワード: ns2, gbvb, virus, protease, viral protein
• 由来する生物種: Hepatitis GB virus B (GBV-B)
• 細胞内の位置: Core protein: Virion (Potential). Envelope glycoprotein E1: Virion membrane; Single-pass type I membrane protein (Potential). Envelope glycoprotein E2: Virion membrane; Single-pass type I membrane protein (Potential). p13: Host endoplasmic reticulum membrane; Multi-pass membrane protein (By similarity). Protease NS2-3: Host endoplasmic reticulum membrane; Multi-pass membrane protein (Potential). Serine protease NS3: Host endoplasmic reticulum membrane; Peripheral membrane protein (By similarity). Non-structural protein 4A: Host endoplasmic reticulum membrane; Single-pass type I membrane protein (Potential). Non-structural protein 4B: Host endoplasmic reticulum membrane; Multi-pass membrane protein (By similarity). Non-structural protein 5A: Host endoplasmic reticulum membrane; Peripheral membrane protein (By similarity). RNA-directed RNA polymerase: Host endoplasmic reticulum membrane; Single-pass type I membrane protein (Potential): Q69422
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 3116.61

構造登録者

Montserret, R.,Martin, A.,Penin, F. (登録日: 2014-02-04, 公開日: 2014-05-07, 最終更新日: 2024-05-15)

• 主引用文献: Boukadida, C.,Marnata, C.,Montserret, R.,Cohen, L.,Blumen, B.,Gouttenoire, J.,Moradpour, D.,Penin, F.,Martin, A.; NS2 Proteins of GB Virus B and Hepatitis C Virus Share Common Protease Activities and Membrane Topologies.; J.Virol., 88:7426-7444, 2014; PubMed: 24741107; DOI: 10.1128/JVI.00656-14

実験手法

SOLUTION NMR