2MGY
Solution structure of the mitochondrial translocator protein (TSPO) in complex with its high-affinity ligand PK11195
Summary for 2MGY
| Entry DOI | 10.2210/pdb2mgy/pdb |
| NMR Information | BMRB: 19608 |
| Descriptor | Translocator protein, N-[(2R)-butan-2-yl]-1-(2-chlorophenyl)-N-methylisoquinoline-3-carboxamide (2 entities in total) |
| Functional Keywords | membrane protein, translocator protein (tspo), protein-ligand complex, mitochondrial membrane, pk11195, dpc micelles, peripheral benzodiazepine receptor, helical membrane channel protein |
| Biological source | Mus musculus (mouse) |
| Total number of polymer chains | 1 |
| Total formula weight | 19151.54 |
| Authors | Jaremko, M.,Jaremko, L.,Giller, K.,Becker, S.,Zweckstetter, M. (deposition date: 2013-11-11, release date: 2014-04-02, Last modification date: 2023-06-14) |
| Primary citation | Jaremko, L.,Jaremko, M.,Giller, K.,Becker, S.,Zweckstetter, M. Structure of the mitochondrial translocator protein in complex with a diagnostic ligand. Science, 343:1363-1366, 2014 Cited by PubMed: 24653034DOI: 10.1126/science.1248725 PDB entries with the same primary citation |
| Experimental method | SOLUTION NMR |
Structure validation
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