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2ME1

HIV-1 gp41 clade B double alanine mutant Membrane Proximal External Region peptide in DPC micelle

Summary for 2ME1
Entry DOI10.2210/pdb2me1/pdb
Related2ME2 2ME3 2ME4 2PV6
NMR InformationBMRB: 19512
DescriptorGp41 (1 entity in total)
Functional Keywordsmper, viral fusion, helix-hinge-helix, membrane protein
Biological sourceHuman immunodeficiency virus 1
Cellular locationTransmembrane protein gp41: Virion membrane; Single-pass type I membrane protein. Surface protein gp120: Virion membrane; Peripheral membrane protein: P04578
Total number of polymer chains1
Total formula weight3455.95
Authors
Sun, Z.J.,Wagner, G.,Reinherz, E.L.,Kim, M.,Song, L.,Choi, J.,Cheng, Y.,Chowdhury, B.,Bellot, G.,Shih, W. (deposition date: 2013-09-20, release date: 2013-10-09, Last modification date: 2023-06-14)
Primary citationSun, Z.Y.,Cheng, Y.,Kim, M.,Song, L.,Choi, J.,Kudahl, U.J.,Brusic, V.,Chowdhury, B.,Yu, L.,Seaman, M.S.,Bellot, G.,Shih, W.M.,Wagner, G.,Reinherz, E.L.
Disruption of Helix-Capping Residues 671 and 674 Reveals a Role in HIV-1 Entry for a Specialized Hinge Segment of the Membrane Proximal External Region of gp41.
J.Mol.Biol., 426:1095-1108, 2014
Cited by
PubMed: 24075869
DOI: 10.1016/j.jmb.2013.09.030
PDB entries with the same primary citation
Experimental method
SOLUTION NMR
Structure validation

217705

건을2024-03-27부터공개중

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