2M8S
NMR Structure of the Cytoplasmic Tail of the Membrane Form of Heparin-binding EGF-like Growth Factor (proHB-EGF-CT) Complexed with the Ubiquitin Homology Domain of Bcl-2-associated Athanogene 1 from Mus musculus (mBAG-1-UBH)
Summary for 2M8S
Entry DOI | 10.2210/pdb2m8s/pdb |
NMR Information | BMRB: 18416 |
Descriptor | BAG family molecular chaperone regulator 1, Proheparin-binding EGF-like growth factor (2 entities in total) |
Functional Keywords | mbag-1, prohb-egf-ct, chaperone-membrane protein complex, chaperone/membrane protein |
Biological source | Mus musculus (mouse) More |
Cellular location | Isoform 1: Nucleus. Isoform 2: Cytoplasm: Q60739 Heparin-binding EGF-like growth factor: Secreted, extracellular space. Proheparin-binding EGF-like growth factor: Cell membrane; Single-pass type I membrane protein: Q99075 |
Total number of polymer chains | 2 |
Total formula weight | 13682.59 |
Authors | Huang, H.W.,Yu, C. (deposition date: 2013-06-03, release date: 2014-04-16, Last modification date: 2024-05-01) |
Primary citation | Hung, K.W.,Huang, H.W.,Cho, C.C.,Chang, S.C.,Yu, C. Nuclear Magnetic Resonance Structure of the Cytoplasmic Tail of Heparin Binding EGF-like Growth Factor (proHB-EGF-CT) Complexed with the Ubiquitin Homology Domain of Bcl-2-Associated Athanogene 1 from Mus musculus (mBAG-1-UBH). Biochemistry, 53:1935-1946, 2014 Cited by PubMed: 24628338DOI: 10.1021/bi5003019 PDB entries with the same primary citation |
Experimental method | SOLUTION NMR |
Structure validation
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