2M8S

NMR Structure of the Cytoplasmic Tail of the Membrane Form of Heparin-binding EGF-like Growth Factor (proHB-EGF-CT) Complexed with the Ubiquitin Homology Domain of Bcl-2-associated Athanogene 1 from Mus musculus (mBAG-1-UBH)

2M8S の概要

• エントリーDOI: 10.2210/pdb2m8s/pdb
• NMR情報: BMRB: 18416
• 分子名称: BAG family molecular chaperone regulator 1, Proheparin-binding EGF-like growth factor (2 entities in total)
• 機能のキーワード: mbag-1, prohb-egf-ct, chaperone-membrane protein complex, chaperone/membrane protein
• 由来する生物種: Mus musculus (mouse); 詳細
• 細胞内の位置: Isoform 1: Nucleus. Isoform 2: Cytoplasm: Q60739; Heparin-binding EGF-like growth factor: Secreted, extracellular space. Proheparin-binding EGF-like growth factor: Cell membrane; Single-pass type I membrane protein: Q99075
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 13682.59

構造登録者

Huang, H.W.,Yu, C. (登録日: 2013-06-03, 公開日: 2014-04-16, 最終更新日: 2024-05-01)

• 主引用文献: Hung, K.W.,Huang, H.W.,Cho, C.C.,Chang, S.C.,Yu, C.; Nuclear Magnetic Resonance Structure of the Cytoplasmic Tail of Heparin Binding EGF-like Growth Factor (proHB-EGF-CT) Complexed with the Ubiquitin Homology Domain of Bcl-2-Associated Athanogene 1 from Mus musculus (mBAG-1-UBH).; Biochemistry, 53:1935-1946, 2014; PubMed: 24628338; DOI: 10.1021/bi5003019

実験手法

SOLUTION NMR