2LZL

FGFR3tm

Summary for 2LZL

• Entry DOI: 10.2210/pdb2lzl/pdb
• NMR Information: BMRB: 18763
• Descriptor: Fibroblast growth factor receptor 3 (1 entity in total)
• Functional Keywords: transmembrane domain, fibroblast growth factor receptor, dimerization, tyrosine kinase, membrane protein
• Biological source: Homo sapiens (human)
• Cellular location: Isoform 1: Cell membrane; Single-pass type I membrane protein. Isoform 2: Cell membrane; Single-pass type I membrane protein (By similarity). Isoform 3: Secreted. Isoform 4: Cell membrane; Single-pass type I membrane protein (By similarity): P22607
• Total number of polymer chains: 2
• Total formula weight: 9208.65

Authors

Lesovoy, D.M.,Bocharov, E.V.,Goncharuk, S.A.,Arseniev, A.S. (deposition date: 2012-10-04, release date: 2013-10-09, Last modification date: 2013-11-27)

• Primary citation: Bocharov, E.V.,Lesovoy, D.M.,Goncharuk, S.A.,Goncharuk, M.V.,Hristova, K.,Arseniev, A.S.; Structure of FGFR3 Transmembrane Domain Dimer: Implications for Signaling and Human Pathologies.; Structure, 21:2087-2093, 2013; PubMed: 24120763; DOI: 10.1016/j.str.2013.08.026

Experimental method

SOLUTION NMR