2LOZ

The novel binding mode of DLC1 and Tensin2 PTB domain

2LOZ の概要

• エントリーDOI: 10.2210/pdb2loz/pdb
• NMR情報: BMRB: 17364
• 分子名称: Tensin-like C1 domain-containing phosphatase, Rho GTPase-activating protein 7 (2 entities in total)
• 機能のキーワード: ptb, dlc1, hydrolase-hydrolase activator complex, hydrolase/hydrolase activator
• 由来する生物種: Homo sapiens (human); 詳細
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 17540.86

構造登録者

Liu, C.,Chen, L.,Zhu, G. (登録日: 2012-01-29, 公開日: 2012-06-06, 最終更新日: 2023-06-14)

• 主引用文献: Chen, L.,Liu, C.,Ko, F.C.,Xu, N.,Ng, I.O.,Yam, J.W.,Zhu, G.; Solution structure of the phosphotyrosine binding (PTB) domain of human tensin2 protein in complex with deleted in liver cancer 1 (DLC1) peptide reveals a novel peptide binding mode.; J.Biol.Chem., 287:26104-26114, 2012; PubMed: 22645138; DOI: 10.1074/jbc.M112.360206

実験手法

SOLUTION NMR