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2LEJ

human prion protein mutant HuPrP(90-231, M129, V210I)

Summary for 2LEJ
Entry DOI10.2210/pdb2lej/pdb
Related1QM1
NMR InformationBMRB: 17714
DescriptorMajor prion protein (1 entity in total)
Functional Keywordspathologic mutant, membrane protein
Biological sourceHomo sapiens (human)
Cellular locationCell membrane; Lipid-anchor, GPI-anchor. Isoform 2: Cytoplasm: P04156
Total number of polymer chains1
Total formula weight16654.56
Authors
Biljan, I.,Ilc, G.,Giachin, G.,Raspadori, A.,Zhukov, I.,Plavec, J.,Legname, G. (deposition date: 2011-06-16, release date: 2011-08-17, Last modification date: 2023-06-14)
Primary citationBiljan, I.,Ilc, G.,Giachin, G.,Raspadori, A.,Zhukov, I.,Plavec, J.,Legname, G.
Toward the Molecular Basis of Inherited Prion Diseases: NMR Structure of the Human Prion Protein with V210I Mutation.
J.Mol.Biol., 412:660-673, 2011
Cited by
PubMed: 21839748
DOI: 10.1016/j.jmb.2011.07.067
PDB entries with the same primary citation
Experimental method
SOLUTION NMR
Structure validation

217705

건을2024-03-27부터공개중

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