2LEJ
human prion protein mutant HuPrP(90-231, M129, V210I)
Summary for 2LEJ
Entry DOI | 10.2210/pdb2lej/pdb |
Related | 1QM1 |
NMR Information | BMRB: 17714 |
Descriptor | Major prion protein (1 entity in total) |
Functional Keywords | pathologic mutant, membrane protein |
Biological source | Homo sapiens (human) |
Cellular location | Cell membrane; Lipid-anchor, GPI-anchor. Isoform 2: Cytoplasm: P04156 |
Total number of polymer chains | 1 |
Total formula weight | 16654.56 |
Authors | Biljan, I.,Ilc, G.,Giachin, G.,Raspadori, A.,Zhukov, I.,Plavec, J.,Legname, G. (deposition date: 2011-06-16, release date: 2011-08-17, Last modification date: 2023-06-14) |
Primary citation | Biljan, I.,Ilc, G.,Giachin, G.,Raspadori, A.,Zhukov, I.,Plavec, J.,Legname, G. Toward the Molecular Basis of Inherited Prion Diseases: NMR Structure of the Human Prion Protein with V210I Mutation. J.Mol.Biol., 412:660-673, 2011 Cited by PubMed: 21839748DOI: 10.1016/j.jmb.2011.07.067 PDB entries with the same primary citation |
Experimental method | SOLUTION NMR |
Structure validation
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