2LDM
Solution structure of human PHF20 Tudor2 domain bound to a p53 segment containing a dimethyllysine analog p53K370me2
Summary for 2LDM
Entry DOI | 10.2210/pdb2ldm/pdb |
NMR Information | BMRB: 17673 |
Descriptor | Uncharacterized protein (1 entity in total) |
Functional Keywords | phf20, tudor domain, epigenetics, methylated p53, transcription factor, transcription-protein binding complex, transcription/protein binding |
Biological source | Homo sapiens |
Total number of polymer chains | 1 |
Total formula weight | 9070.21 |
Authors | Cui, G.,Botuyan, M.,Mer, G. (deposition date: 2011-05-30, release date: 2012-05-30, Last modification date: 2023-11-15) |
Primary citation | Cui, G.,Park, S.,Badeaux, A.I.,Kim, D.,Lee, J.,Thompson, J.R.,Yan, F.,Kaneko, S.,Yuan, Z.,Botuyan, M.V.,Bedford, M.T.,Cheng, J.Q.,Mer, G. PHF20 is an effector protein of p53 double lysine methylation that stabilizes and activates p53. Nat.Struct.Mol.Biol., 19:916-924, 2012 Cited by PubMed: 22864287DOI: 10.1038/nsmb.2353 PDB entries with the same primary citation |
Experimental method | SOLUTION NMR |
Structure validation
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