2LDM

Solution structure of human PHF20 Tudor2 domain bound to a p53 segment containing a dimethyllysine analog p53K370me2

2LDM の概要

• エントリーDOI: 10.2210/pdb2ldm/pdb
• NMR情報: BMRB: 17673
• 分子名称: Uncharacterized protein (1 entity in total)
• 機能のキーワード: phf20, tudor domain, epigenetics, methylated p53, transcription factor, transcription-protein binding complex, transcription/protein binding
• 由来する生物種: Homo sapiens
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 9070.21

構造登録者

Cui, G.,Botuyan, M.,Mer, G. (登録日: 2011-05-30, 公開日: 2012-05-30, 最終更新日: 2023-11-15)

• 主引用文献: Cui, G.,Park, S.,Badeaux, A.I.,Kim, D.,Lee, J.,Thompson, J.R.,Yan, F.,Kaneko, S.,Yuan, Z.,Botuyan, M.V.,Bedford, M.T.,Cheng, J.Q.,Mer, G.; PHF20 is an effector protein of p53 double lysine methylation that stabilizes and activates p53.; Nat.Struct.Mol.Biol., 19:916-924, 2012; PubMed: 22864287; DOI: 10.1038/nsmb.2353

実験手法

SOLUTION NMR