2LAG

Structure of the 44 kDa complex of interferon-alpha2 with the extracellular part of IFNAR2 obtained by 2D-double difference NOESY

2LAG の概要

• エントリーDOI: 10.2210/pdb2lag/pdb
• 関連するPDBエントリー: 1kz1
• NMR情報: BMRB: 16677
• 分子名称: Interferon alpha/beta receptor 2, Interferon alpha-2 (2 entities in total)
• 機能のキーワード: interferon, receptor, immune system
• 由来する生物種: Homo sapiens (human); 詳細
• 細胞内の位置: Secreted: P48551; Isoform 1: Membrane; Single-pass type I membrane protein. Isoform 2: Membrane; Single-pass type I membrane protein. Isoform 3: Secreted: P01563
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 43587.53

構造登録者

Nudelman, I.,Akabayov, S.R.,Scherf, T.,Anglister, J. (登録日: 2011-03-13, 公開日: 2011-08-17, 最終更新日: 2011-09-28)

• 主引用文献: Nudelman, I.,Akabayov, S.R.,Scherf, T.,Anglister, J.; Observation of Intermolecular Interactions in Large Protein Complexes by 2D-Double Difference Nuclear Overhauser Enhancement Spectroscopy: Application to the 44 kDa Interferon-Receptor Complex.; J.Am.Chem.Soc., 133:14755-14764, 2011; PubMed: 21819146; DOI: 10.1021/ja205480v

実験手法

SOLUTION NMR