2L2V

NMR Solution Structures of -3 (3' staggered) Bistranded Abasic Site Lesions in DNA

Summary for 2L2V

• Entry DOI: 10.2210/pdb2l2v/pdb
• Related: 1yct 1ycw
• Descriptor: DNA_(5'-D(*CP*AP*GP*CP*TP*AP*TP*GP*(3DR)P*GP*AP*AP*GP*C)-3')_, DNA_(5'-D(*GP*CP*TP*TP*CP*AP*CP*AP*(3DR)P*AP*GP*CP*TP*G)-3')_ (2 entities in total)
• Functional Keywords: abasic lesion, bistranded dna lesions, clustered dna damage, multiple dna damage, ionizing radiation, dna
• Total number of polymer chains: 2
• Total formula weight: 8312.40

Authors

Hazel, R.D.,de los Santos, C. (deposition date: 2010-08-27, release date: 2011-07-13, Last modification date: 2024-05-01)

• Primary citation: Hazel, R.D.,de los Santos, C.; NMR solution structures of clustered abasic site lesions in DNA: structural differences between 3'-staggered (-3) and 5'-staggered (+3) bistranded lesions.; Biochemistry, 49:8978-8987, 2010; PubMed: 20825249; DOI: 10.1021/bi101021e

Experimental method

SOLUTION NMR