2L1M

Solution structure of the eag domain of the hERG (Kv11.1) K+ channel

Summary for 2L1M

• Entry DOI: 10.2210/pdb2l1m/pdb
• Related: 1byw
• Descriptor: Potassium voltage-gated channel subfamily H member 2 (1 entity in total)
• Functional Keywords: eag domain, herg, kv11.1, pas domain, transport protein
• Biological source: Homo sapiens (human)
• Cellular location: Membrane; Multi-pass membrane protein: Q12809
• Total number of polymer chains: 1
• Total formula weight: 17251.90

Authors

Muskett, F.W.,Mitcheson, J.S. (deposition date: 2010-07-29, release date: 2011-01-19, Last modification date: 2011-07-13)

• Primary citation: Muskett, F.W.,Thouta, S.,Thomson, S.J.,Bowen, A.,Stansfeld, P.J.,Mitcheson, J.S.; Mechanistic insight into human ether-a-go-go-related gene (hERG) K+ channel deactivation gating from the solution structure of the EAG domain.; J.Biol.Chem., 286:6184-6191, 2011; PubMed: 21135103; DOI: 10.1074/jbc.M110.199364

Experimental method

SOLUTION NMR