2KY8

Solution structure and dynamic analysis of chicken MBD2 methyl binding domain bound to a target methylated DNA sequence

Summary for 2KY8

• Entry DOI: 10.2210/pdb2ky8/pdb
• Related: 1IG4 3C2I
• NMR Information: BMRB: 16936
• Descriptor: Methyl-CpG-binding domain protein 2, DNA (5'-D(*GP*GP*AP*AP*TP*(5CM)P*GP*GP*CP*(TED)P*C)-3'), DNA (5'-D(*GP*AP*GP*CP*(5CM)P*GP*AP*TP*(TED)P*CP*C)-3'), ... (4 entities in total)
• Functional Keywords: dna binding domain, transcription-dna complex, transcription/dna
• Biological source: Gallus gallus (bantam,chickens)
• Total number of polymer chains: 3
• Total formula weight: 15596.19

Authors

Williams Jr., D.C.,Scarsdale Jr., J.N. (deposition date: 2010-05-18, release date: 2011-05-18, Last modification date: 2020-02-05)

• Primary citation: Scarsdale, J.N.,Webb, H.D.,Ginder, G.D.,Williams, D.C.; Solution structure and dynamic analysis of chicken MBD2 methyl binding domain bound to a target-methylated DNA sequence.; Nucleic Acids Res., 39:6741-6752, 2011; PubMed: 21531701; DOI: 10.1093/nar/gkr262

Experimental method

SOLUTION NMR