2KUP

Solution structure of the complex of the PTB domain of SNT-2 and 19-residue peptide (aa 1571-1589) of HALK

Summary for 2KUP

• Entry DOI: 10.2210/pdb2kup/pdb
• Related: 2YS5
• Descriptor: Fibroblast growth factor receptor substrate 3, 19-residue peptide from ALK tyrosine kinase receptor (2 entities in total)
• Functional Keywords: complex, snt-2, ptb domain, halk, structural genomics, signaling protein, nppsfa, national project on protein structural and functional analyses, riken structural genomics/proteomics initiative, rsgi, signaling protein-oncoprotein complex, signaling protein/oncoprotein
• Biological source: Homo sapiens (human); More
• Cellular location: Membrane; Lipid-anchor: O43559; Cell membrane; Single-pass type I membrane protein: Q9UM73
• Total number of polymer chains: 2
• Total formula weight: 18675.92

Authors

Li, H.,Koshiba, S.,Inoue, M.,Kigawa, T.,Yokoyama, S.,RIKEN Structural Genomics/Proteomics Initiative (RSGI) (deposition date: 2010-02-24, release date: 2010-05-26, Last modification date: 2014-02-12)

• Primary citation: Koshiba, S.,Li, H.,Motoda, Y.,Tomizawa, T.,Kasai, T.,Tochio, N.,Yabuki, T.,Harada, T.,Watanabe, S.,Tanaka, A.,Shirouzu, M.,Kigawa, T.,Yamamoto, T.,Yokoyama, S.; Structural basis for the recognition of nucleophosmin-anaplastic lymphoma kinase oncoprotein by the phosphotyrosine binding domain of Suc1-associated neurotrophic factor-induced tyrosine-phosphorylated target-2; J.Struct.Funct.Genom., 11:125-141, 2010; PubMed: 20454865; DOI: 10.1007/s10969-010-9091-x

Experimental method

SOLUTION NMR