2KTZ
Inhibitor Induced Structural Change in the HCV IRES Domain IIa RNA
Summary for 2KTZ
Entry DOI | 10.2210/pdb2ktz/pdb |
Related | 2KU0 |
Descriptor | HCV IRES Domain IIa RNA, (7R)-7-[(dimethylamino)methyl]-1-[3-(dimethylamino)propyl]-7,8-dihydro-1H-furo[3,2-e]benzimidazol-2-amine (2 entities in total) |
Functional Keywords | hepatitis c virus, rna structure, antiviral, rna |
Biological source | Hepatitis C virus (HCV) |
Total number of polymer chains | 1 |
Total formula weight | 12439.60 |
Authors | Paulsen, R.B.,Seth, P.P.,Swayze, E.E.,Griffey, R.H.,Skalicky, J.J.,Cheatham III, T.E.,Davis, D.R. (deposition date: 2010-02-10, release date: 2010-04-28, Last modification date: 2024-05-22) |
Primary citation | Paulsen, R.B.,Seth, P.P.,Swayze, E.E.,Griffey, R.H.,Skalicky, J.J.,Cheatham, T.E.,Davis, D.R. Inhibitor-induced structural change in the HCV IRES domain IIa RNA. Proc.Natl.Acad.Sci.USA, 107:7263-7268, 2010 Cited by PubMed: 20360559DOI: 10.1073/pnas.0911896107 PDB entries with the same primary citation |
Experimental method | SOLUTION NMR |
Structure validation
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