2KTD

Solution structure of mouse lipocalin-type prostaglandin D synthase / substrate analog (U-46619) complex

2KTD の概要

• エントリーDOI: 10.2210/pdb2ktd/pdb
• 分子名称: Prostaglandin-H2 D-isomerase, (5Z)-7-{(1R,4S,5S,6R)-6-[(1E,3S)-3-hydroxyoct-1-en-1-yl]-2-oxabicyclo[2.2.1]hept-5-yl}hept-5-enoic acid (2 entities in total)
• 機能のキーワード: lipocalin-type prostaglandin d synthase, l-pgds, prostaglandin h2, prostaglandin d2, u-46619, lipocalin, disulfide bond, endoplasmic reticulum, fatty acid biosynthesis, glycoprotein, golgi apparatus, isomerase, lipid synthesis, nucleus, prostaglandin biosynthesis, pyrrolidone carboxylic acid, secreted, transport
• 由来する生物種: Mus musculus (mouse)
• 細胞内の位置: Rough endoplasmic reticulum (By similarity): O09114
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 18936.29

構造登録者

Shimamoto, S.,Maruo, H.,Yoshida, T.,Kato, N.,Ohkubo, T. (登録日: 2010-01-27, 公開日: 2011-02-02, 最終更新日: 2024-05-01)

• 主引用文献: Shimamoto, S.,Maruo, H.,Yoshida, T.,Inui, T.,Miyamoto, Y.,Kobayashi, Y.,Tsurumura, T.,Aritake, K.,Urade, Y.,Ohkubo, T.; Solution Structure of Lipocalin-type Prostaglandin D synthase / Substrate analog complex reveals Open-Closed Conformational Change required for Substrate Recognition; To be Published,

実験手法

SOLUTION NMR