2KSO
EphA2:SHIP2 SAM:SAM complex
Summary for 2KSO
| Entry DOI | 10.2210/pdb2kso/pdb |
| Descriptor | Ephrin type-A receptor 2, Phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase 2 (2 entities in total) |
| Functional Keywords | sam domain, heterodimer, cell signaling, angiogenesis, apoptosis, atp-binding, cataract, disulfide bond, glycoprotein, kinase, membrane, nucleotide-binding, phosphoprotein, receptor, transferase, transmembrane, tyrosine-protein kinase, actin-binding, cell adhesion, cytoskeleton, diabetes mellitus, hydrolase, immune response, sh2 domain, sh3-binding, protein binding |
| Biological source | Homo sapiens (human) More |
| Cellular location | Cell membrane; Single-pass type I membrane protein: P29317 Cytoplasm, cytosol: O15357 |
| Total number of polymer chains | 2 |
| Total formula weight | 18073.36 |
| Authors | Hota, P.K.,Preeti, C.,Stetzik, L.,Kim, S.,Wang, B.,Lee, H.,Buck, M. (deposition date: 2010-01-10, release date: 2011-07-27, Last modification date: 2024-05-01) |
| Primary citation | Lee, H.,Hota, P.,Preeti, C.,Wang, B.,Buck, M. Structure and function of the EphA2:SHIP2 SAM domain heterodimer To be Published, |
| Experimental method | SOLUTION NMR |
Structure validation
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