2KSO

EphA2:SHIP2 SAM:SAM complex

2KSO の概要

• エントリーDOI: 10.2210/pdb2kso/pdb
• 分子名称: Ephrin type-A receptor 2, Phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase 2 (2 entities in total)
• 機能のキーワード: sam domain, heterodimer, cell signaling, angiogenesis, apoptosis, atp-binding, cataract, disulfide bond, glycoprotein, kinase, membrane, nucleotide-binding, phosphoprotein, receptor, transferase, transmembrane, tyrosine-protein kinase, actin-binding, cell adhesion, cytoskeleton, diabetes mellitus, hydrolase, immune response, sh2 domain, sh3-binding, protein binding
• 由来する生物種: Homo sapiens (human); 詳細
• 細胞内の位置: Cell membrane; Single-pass type I membrane protein: P29317; Cytoplasm, cytosol: O15357
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 18073.36

構造登録者

Hota, P.K.,Preeti, C.,Stetzik, L.,Kim, S.,Wang, B.,Lee, H.,Buck, M. (登録日: 2010-01-10, 公開日: 2011-07-27, 最終更新日: 2024-05-01)

• 主引用文献: Lee, H.,Hota, P.,Preeti, C.,Wang, B.,Buck, M.; Structure and function of the EphA2:SHIP2 SAM domain heterodimer; To be Published,

実験手法

SOLUTION NMR