2KRD
Solution Structure of the Regulatory Domain of Human Cardiac Troponin C in Complex with the Switch Region of cardiac Troponin I and W7
Summary for 2KRD
Entry DOI | 10.2210/pdb2krd/pdb |
Descriptor | Troponin C, slow skeletal and cardiac muscles, Troponin I, cardiac muscle, CALCIUM ION, ... (4 entities in total) |
Functional Keywords | cardiac troponin c, regulatory domain, troponin i, switch region, w7, acetylation, calcium, cardiomyopathy, disease mutation, muscle protein, polymorphism, actin-binding, phosphoprotein, structural protein |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 2 |
Total formula weight | 12257.43 |
Authors | Oleszczuk, M.,Robertson, I.M.,Li, M.X.,Sykes, B.D. (deposition date: 2009-12-16, release date: 2010-02-16, Last modification date: 2024-05-22) |
Primary citation | Oleszczuk, M.,Robertson, I.M.,Li, M.X.,Sykes, B.D. Solution structure of the regulatory domain of human cardiac troponin C in complex with the switch region of cardiac troponin I and W7: the basis of W7 as an inhibitor of cardiac muscle contraction. J.MOL.CELL.CARDIOL., 48:925-933, 2010 Cited by PubMed: 20116385DOI: 10.1016/j.yjmcc.2010.01.016 PDB entries with the same primary citation |
Experimental method | SOLUTION NMR |
Structure validation
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