2KQS

Phosphorylation of SUMO-interacting motif by CK2 enhances Daxx SUMO binding activity

Summary for 2KQS

Entry DOI	10.2210/pdb2kqs/pdb
Related	2ASQ 2RPQ
Descriptor	Small ubiquitin-related modifier 1, Death domain-associated protein 6 (2 entities in total)
Functional Keywords	sumo, sim, daxx, nucleus, phosphoprotein, ubl conjugation pathway, apoptosis, transcription, transcription regulation
Biological source	Homo sapiens (human) More
Cellular location	Nucleus membrane: P63165 Cytoplasm: Q9UER7
Total number of polymer chains	2
Total formula weight	13589.13
Authors	Naik, M.T.,Huang, T.H.,Shih, H. (deposition date: 2009-11-17, release date: 2010-12-01, Last modification date: 2013-08-21)
Primary citation	Chang, C.C.,Naik, M.T.,Huang, Y.S.,Jeng, J.C.,Liao, P.H.,Kuo, H.Y.,Ho, C.C.,Hsieh, Y.L.,Lin, C.H.,Huang, N.J.,Naik, N.M.,Kung, C.C.,Lin, S.Y.,Chen, R.H.,Chang, K.S.,Huang, T.H.,Shih, H.M. Structural and functional roles of Daxx SIM phosphorylation in SUMO paralog-selective binding and apoptosis modulation. Mol.Cell, 42:62-74, 2011 Cited by PubMed: 21474068 DOI: 10.1016/j.molcel.2011.02.022 PDB entries with the same primary citation
Experimental method	SOLUTION NMR

Structure validation