2KOY

Structure of the E1064A mutant of the N-domain of Wilson Disease Associated Protein

2KOY の概要

• エントリーDOI: 10.2210/pdb2koy/pdb
• 関連するPDBエントリー: 2ARF
• NMR情報: BMRB: 16536
• 分子名称: Copper-transporting ATPase 2 (1 entity in total)
• 機能のキーワード: atp7b, wilson disease, atpase, copper transport, atp binding, atp-binding, disease mutation, golgi apparatus, hydrolase, ion transport, magnesium, membrane, metal-binding, mitochondrion, nucleotide-binding, phosphoprotein, transmembrane, transport, metal transport
• 由来する生物種: Homo sapiens (human)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 14752.18

構造登録者

Dmitriev, O.Y. (登録日: 2009-10-03, 公開日: 2010-12-15, 最終更新日: 2024-05-22)

• 主引用文献: Dmitriev, O.Y.,Bhattacharjee, A.,Nokhrin, S.,Uhlemann, E.M.,Lutsenko, S.; Difference in stability of the N-domain underlies distinct intracellular properties of the E1064A and H1069Q mutants of copper-transporting ATPase ATP7B.; J. Biol. Chem., 286:16355-16362, 2011; PubMed: 21398519; DOI: 10.1074/jbc.M110.198101

実験手法

SOLUTION NMR