2KNK

Structure of the trimethylene N2-dG:N2-dG interstrand cross-link in 5'-CpG-3' sequence context

Summary for 2KNK

• Entry DOI: 10.2210/pdb2knk/pdb
• Related: 1HZ2 2KNL
• Descriptor: DNA (5'-D(*AP*GP*GP*CP*GP*CP*CP*T)-3'), PROPANE (2 entities in total)
• Functional Keywords: interstrand cross-link, trimethylene, cpg sequence context, dna
• Total number of polymer chains: 2
• Total formula weight: 4899.31

Authors

Huang, H.,Dooley, P.A.,Harris, C.M.,Harris, T.M.,Stone, M.P. (deposition date: 2009-08-26, release date: 2009-09-29, Last modification date: 2022-03-16)

• Primary citation: Huang, H.,Dooley, P.A.,Harris, C.M.,Harris, T.M.,Stone, M.P.; Differential base stacking interactions induced by trimethylene interstrand DNA cross-links in the 5'-CpG-3' and 5'-GpC-3' sequence contexts.; Chem.Res.Toxicol., 22:1810-1816, 2009; PubMed: 19916525; DOI: 10.1021/tx900225c

Experimental method

SOLUTION NMR