2KI4

FGF1-S100A13 complex structure: key component in non-classical path way of FGF1

2KI4 の概要

• エントリーDOI: 10.2210/pdb2ki4/pdb
• 関連するPDBエントリー: 2KI6
• 分子名称: Heparin-binding growth factor 1, Protein S100-A13 (3 entities in total)
• 機能のキーワード: acidic fibroblast growth factor, s100a13, tetrameric complex, acetylation, alternative splicing, angiogenesis, developmental protein, differentiation, growth factor, heparin-binding, mitogen, polymorphism, calcium, protein transport
• 由来する生物種: Homo sapiens (human); 詳細
• 細胞内の位置: Secreted: P05230; Cytoplasm: Q99584 Q99584
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 53213.45

構造登録者

Krishna, S.M.,Rani, S.G.,Yu, C. (登録日: 2009-04-27, 公開日: 2010-03-09, 最終更新日: 2011-07-13)

• 主引用文献: Mohan, S.K.,Rani, S.G.,Yu, C.; The heterohexameric complex structure, a component in the non-classical pathway for fibroblast growth factor 1 (FGF1) secretion.; J.Biol.Chem., 285:15464-15475, 2010; PubMed: 20220137; DOI: 10.1074/jbc.M109.066357

実験手法

SOLUTION NMR