2KGE
NMR Solution Structures of 3,5-dioxohexyl ACP (a triketide mimic) from the actinorhodin polyketide synthase in Streptomyces coelicolor
Summary for 2KGE
Entry DOI | 10.2210/pdb2kge/pdb |
Related | 2k0x 2k0y 2kg6 2kg8 2kg9 2kga 2kgc 2kgd |
NMR Information | BMRB: 16203 |
Descriptor | Actinorhodin polyketide synthase acyl carrier protein, N-{2-[(3,5-dioxohexyl)sulfanyl]ethyl}-N~3~-[(2S)-2-hydroxy-3,3-dimethyl-4-(phosphonooxy)butanoyl]-beta-alaninamide (2 entities in total) |
Functional Keywords | acp, triketide, polyketide, actinorhodin, antibiotic biosynthesis, phosphopantetheine, biosynthetic protein |
Biological source | Streptomyces coelicolor |
Total number of polymer chains | 1 |
Total formula weight | 9709.65 |
Authors | Crump, M.P.,Evans, S.E.,Williams, C. (deposition date: 2009-03-08, release date: 2009-04-14, Last modification date: 2021-10-20) |
Primary citation | Evans, S.E.,Williams, C.,Arthur, C.J.,Ploskon, E.,Wattana-Amorn, P.,Cox, R.J.,Crosby, J.,Willis, C.L.,Simpson, T.J.,Crump, M.P. Probing the Interactions of Early Polyketide Intermediates with the Actinorhodin ACP from S. coelicolor A3(2). J.Mol.Biol., 389:511-528, 2009 Cited by PubMed: 19361520DOI: 10.1016/j.jmb.2009.03.072 PDB entries with the same primary citation |
Experimental method | SOLUTION NMR |
Structure validation
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