2KEI
Refined Solution Structure of a Dimer of LAC repressor DNA-Binding domain complexed to its natural operator O1
Summary for 2KEI
Entry DOI | 10.2210/pdb2kei/pdb |
Related | 1L1M 2KEJ 2KEK |
Descriptor | Lactose operon repressor, DNA (5'-D(*GP*AP*AP*TP*TP*GP*TP*GP*AP*GP*CP*GP*GP*AP*TP*AP*AP*CP*AP*AP*TP*TP*T)-3'), DNA (5'-D(P*AP*AP*AP*TP*TP*GP*TP*TP*AP*TP*CP*CP*GP*CP*TP*CP*AP*CP*AP*AP*TP*TP*C)-3') (3 entities in total) |
Functional Keywords | lac repressor, lac operators, protein-dna complex, dna-binding, repressor, transcription, transcription regulation, transcription-dna complex, transcription/dna |
Biological source | Escherichia coli |
Total number of polymer chains | 4 |
Total formula weight | 27763.69 |
Authors | Romanuka, J.,Folkers, G.,Biris, N.,Tishchenko, E.,Wienk, H.,Kaptein, R.,Boelens, R. (deposition date: 2009-01-30, release date: 2009-05-19, Last modification date: 2021-10-20) |
Primary citation | Romanuka, J.,Folkers, G.E.,Biris, N.,Tishchenko, E.,Wienk, H.,Bonvin, A.M.,Kaptein, R.,Boelens, R. Specificity and affinity of Lac repressor for the auxiliary operators O2 and O3 are explained by the structures of their protein-DNA complexes. J.Mol.Biol., 390:478-489, 2009 Cited by PubMed: 19450607DOI: 10.1016/j.jmb.2009.05.022 PDB entries with the same primary citation |
Experimental method | SOLUTION NMR |
Structure validation
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