2KDH

The Solution Structure of Human Cardiac Troponin C in complex with the Green Tea Polyphenol; (-)-epigallocatechin-3-gallate

2KDH の概要

• エントリーDOI: 10.2210/pdb2kdh/pdb
• NMR情報: BMRB: 17243
• 分子名称: Troponin C, slow skeletal and cardiac muscles, CALCIUM ION, (2R,3R)-5,7-dihydroxy-2-(3,4,5-trihydroxyphenyl)-3,4-dihydro-2H-chromen-3-yl 3,4,5-trihydroxybenzoate (3 entities in total)
• 機能のキーワード: ca2+ binding protein, ca2+ sensitizer, troponin c, egcg, acetylation, calcium, cardiomyopathy, disease mutation, muscle protein, polymorphism, structural protein
• 由来する生物種: Homo sapiens (human)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 8907.73

構造登録者

Robertson, I.M.,Li, M.X.,Sykes, B.D. (登録日: 2009-01-09, 公開日: 2009-06-16, 最終更新日: 2024-05-22)

• 主引用文献: Robertson, I.M.,Li, M.X.,Sykes, B.D.; Solution structure of human cardiac troponin C in complex with the green tea polyphenol, (-)-epigallocatechin 3-gallate; J.Biol.Chem., 284:23012-23023, 2009; PubMed: 19542563; DOI: 10.1074/jbc.M109.021352

実験手法

SOLUTION NMR