2K8T

Solution NMR structure of trans-4-hydroxynonenal derived dG adduct of (6R,8S,11R)-configuration opposite dC

Summary for 2K8T

Related2K8U
Descriptor5'-D(*DGP*DCP*DTP*DAP*DGP*DCP*DGP*DAP*DGP*DTP*DCP*DC)-3', 5'-D(*DGP*DGP*DAP*DCP*DTP*DCP*DGP*DCP*DTP*DAP*DGP*DC)-3', (2S,5R)-5-pentyltetrahydrofuran-2-ol (3 entities in total)
Functional Keywordshne-dg (6r, 8s, 11r), hne derived dg adduct, trans-4-hydroxynonenal, dna
Total number of polymer chains2
Total molecular weight7485.02
Authors
Huang, H.,Wang, H.,Qi, N.,Lloyd, R.S.,Rizzo, C.J.,Stone, M.P. (deposition date: 2008-09-23, release date: 2008-11-04, Last modification date: 2011-07-13)
Primary citation
Huang, H.,Wang, H.,Qi, N.,Lloyd, R.S.,Rizzo, C.J.,Stone, M.P.
The stereochemistry of trans-4-hydroxynonenal-derived exocyclic 1,N2-2'-deoxyguanosine adducts modulates formation of interstrand cross-links in the 5'-CpG-3' sequence.
Biochemistry, 47:11457-11472, 2008
PubMed: 18847226 (PDB entries with the same primary citation)
DOI: 10.1021/bi8011143
MImport into Mendeley
Experimental method
SOLUTION NMR
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Structure validation

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