2K85

p190-A RhoGAP FF1 domain

Summary for 2K85

• Entry DOI: 10.2210/pdb2k85/pdb
• NMR Information: BMRB: 15938
• Descriptor: Glucocorticoid receptor DNA-binding factor 1 (1 entity in total)
• Functional Keywords: ff domain, p190-a rhogap, protein phosphorylation, alternative splicing, anti-oncogene, cell cycle, cytoplasm, dna-binding, gtpase activation, nucleus, phosphoprotein, repressor, transcription, transcription regulation, protein binding
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 1
• Total formula weight: 8173.32

Authors

Bonet, R.,Ruiz, L.,Martin-Malpartida, P.,Macias, M. (deposition date: 2008-09-02, release date: 2009-05-19, Last modification date: 2023-06-14)

• Primary citation: Bonet, R.,Ruiz, L.,Aragon, E.,Martin-Malpartida, P.,Macias, M.J.; NMR structural studies on human p190-A RhoGAPFF1 revealed that domain phosphorylation by the PDGF-receptor alpha requires its previous unfolding.; J.Mol.Biol., 389:230-237, 2009; PubMed: 19393245; DOI: 10.1016/j.jmb.2009.04.035

Experimental method

SOLUTION NMR