2K4U

Solution structure of the SCORPION TOXIN ADWX-1

2K4U の概要

• エントリーDOI: 10.2210/pdb2k4u/pdb
• 分子名称: Potassium channel toxin alpha-KTx 3.6 (1 entity in total)
• 機能のキーワード: kv1.1 channel, kv1.3 channel, channel turret, adwx-1 peptide selectivity, structural basis, amidation, ionic channel inhibitor, neurotoxin, potassium channel inhibitor, secreted, toxin
• 由来する生物種: Mesobuthus martensii (Chinese scorpion)
• 細胞内の位置: Secreted: Q9NII7
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 4088.98

構造登録者

Yin, S.J.,Jiang, L.,Yi, H.,Han, S.,Yang, D.W.,Liu, M.L.,Liu, H.,Cao, Z.J.,Wu, Y.L.,Li, W.X. (登録日: 2008-06-18, 公開日: 2008-12-09, 最終更新日: 2021-11-10)

• 主引用文献: Yin, S.J.,Jiang, L.,Yi, H.,Han, S.,Yang, D.W.,Liu, M.L.,Liu, H.,Cao, Z.J.,Wu, Y.L.,Li, W.X.; Different Residues in Channel Turret Determining the Selectivity of ADWX-1 Inhibitor Peptide between Kv1.1 and Kv1.3 Channels; J.Proteome Res., 7:4890-4897, 2008; PubMed: 18937510; DOI: 10.1021/pr800494a

実験手法

SOLUTION NMR