2K3S

HADDOCK-derived structure of the CH-domain of the smoothelin-like 1 complexed with the C-domain of apocalmodulin

2K3S の概要

• エントリーDOI: 10.2210/pdb2k3s/pdb
• 関連するPDBエントリー: 1F71 2JV9
• 分子名称: Smoothelin-like protein 1, Calmodulin (2 entities in total)
• 機能のキーワード: apocalmodulin complex, calponin homology domain, smoothelin-like 1, haddock model, ch-domain, coiled coil, acetylation, calcium, methylation, protein binding
• 由来する生物種: Mus musculus (mouse); 詳細
• 細胞内の位置: Cytoplasm, myofibril, sarcomere, I band: Q99LM3
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 21431.26

構造登録者

Ishida, H.,Borman, M.A.,Ostrander, J.,Vogel, H.J.,MacDonald, J.A. (登録日: 2008-05-15, 公開日: 2008-05-27, 最終更新日: 2022-03-16)

• 主引用文献: Ishida, H.,Borman, M.A.,Ostrander, J.,Vogel, H.J.,MacDonald, J.A.; Solution structure of the calponin homology (CH) domain from the smoothelin-like 1 protein: a unique apocalmodulin-binding mode and the possible role of the C-terminal type-2 CH-domain in smooth muscle relaxation.; J.Biol.Chem., 283:20569-20578, 2008; PubMed: 18477568; DOI: 10.1074/jbc.M800627200

実験手法

SOLUTION NMR