2K1R

The solution NMR structure of the complex between MNK1 and HAH1 mediated by Cu(I)

2K1R の概要

• エントリーDOI: 10.2210/pdb2k1r/pdb
• 関連するPDBエントリー: 1KVJ 1TL4 3CJK
• 分子名称: Copper-transporting ATPase 1, Copper transport protein ATOX1, COPPER (II) ION (3 entities in total)
• 機能のキーワード: mnk1, hah1, protein-protein interaction, atp7a, spine 2, structural proteomics in europe, alternative splicing, atp-binding, copper, copper transport, cytoplasm, disease mutation, endoplasmic reticulum, glycoprotein, golgi apparatus, hydrolase, ion transport, magnesium, membrane, metal-binding, nucleotide-binding, phosphoprotein, polymorphism, transmembrane, transport, chaperone, hydrolase-chaperone complex, structural genomics, hydrolase/chaperone
• 由来する生物種: Homo sapiens (human); 詳細
• 細胞内の位置: Golgi apparatus, trans-Golgi network membrane; Multi-pass membrane protein. Isoform 3: Cytoplasm, cytosol (Probable). Isoform 5: Endoplasmic reticulum: Q04656
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 15525.36

構造登録者

Bertini, I.,Banci, L.C.,Felli, I.C.,Pavelkova, A.,Rosato, A.,Structural Proteomics in Europe (SPINE) (登録日: 2008-03-14, 公開日: 2009-03-31, 最終更新日: 2022-03-16)

• 主引用文献: Bertini, I.,Banci, L.C.,Felli, I.C.,Pavelkova, A.,Rosato, A.; The solution structure of the copper(I)-mediated complex between the first soluble domain of the Menkes protein and the metallochaperone HAH1.; To be Published,

実験手法

SOLUTION NMR