2JY8
NMR structure of the ubiquitin associated (UBA) domain of p62 (SQSTM1) in complex with ubiquitin. RDC refined
Summary for 2JY8
Entry DOI | 10.2210/pdb2jy8/pdb |
Related | 2JY7 |
NMR Information | BMRB: 15592 |
Descriptor | Ubiquitin-binding protein p62 (1 entity in total) |
Functional Keywords | ubiquitin binding, ubiquitin associated domain, helical bundle, three helices, alternative splicing, apoptosis, cytoplasm, differentiation, disease mutation, endosome, immune response, metal-binding, nucleus, phosphoprotein, polymorphism, zinc, zinc-finger, protein binding |
Biological source | Homo sapiens (human) |
Total number of polymer chains | 1 |
Total formula weight | 5744.41 |
Authors | Long, J.E.,Layfield, R.,Searle, M.S. (deposition date: 2007-12-07, release date: 2007-12-18, Last modification date: 2024-05-01) |
Primary citation | Long, J.,Gallagher, T.R.,Cavey, J.R.,Sheppard, P.W.,Ralston, S.H.,Layfield, R.,Searle, M.S. Ubiquitin Recognition by the Ubiquitin-associated Domain of p62 Involves a Novel Conformational Switch J.Biol.Chem., 283:5427-5440, 2008 Cited by PubMed: 18083707DOI: 10.1074/jbc.M704973200 PDB entries with the same primary citation |
Experimental method | SOLUTION NMR |
Structure validation
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