2JY7

NMR structure of the ubiquitin associated (UBA) domain of p62 (SQSTM1). RDC refined

2JY7 の概要

• エントリーDOI: 10.2210/pdb2jy7/pdb
• 関連するPDBエントリー: 2JY8
• NMR情報: BMRB: 15591
• 分子名称: Ubiquitin-binding protein p62 (1 entity in total)
• 機能のキーワード: ubiquitin binding, ubiquitin associated domain, helical bundle, three helices, alternative splicing, apoptosis, cytoplasm, differentiation, disease mutation, endosome, immune response, metal-binding, nucleus, phosphoprotein, polymorphism, zinc, zinc-finger, protein binding
• 由来する生物種: Homo sapiens (human)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 5744.41

構造登録者

Long, J.E.,Layfield, R.,Searle, M.S. (登録日: 2007-12-07, 公開日: 2007-12-18, 最終更新日: 2024-05-01)

• 主引用文献: Long, J.,Gallagher, T.R.,Cavey, J.R.,Sheppard, P.W.,Ralston, S.H.,Layfield, R.,Searle, M.S.; Ubiquitin Recognition by the Ubiquitin-associated Domain of p62 Involves a Novel Conformational Switch; J.Biol.Chem., 283:5427-5440, 2008; PubMed: 18083707; DOI: 10.1074/jbc.M704973200

実験手法

SOLUTION NMR