2JXZ

Solution Conformation of A Non-Amyloidogenic Analogue of Human Calcitonin in Sodium Dodecyl Sulfate Micelles

2JXZ の概要

• エントリーDOI: 10.2210/pdb2jxz/pdb
• 分子名称: Calcitonin (1 entity in total)
• 機能のキーワード: a-helix, amidation, cleavage on pair of basic residues, hormone, secreted
• 細胞内の位置: Secreted: P01258
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 3455.89

構造登録者

Andreotti, G.,Vitale, R.,Avidan-Shpalter, C.,Amodeo, P.,Gazit, E.,Motta, A. (登録日: 2007-12-03, 公開日: 2008-11-25, 最終更新日: 2011-07-13)

• 主引用文献: Andreotti, G.,Vitale, R.M.,Avidan-Shpalter, C.,Amodeo, P.,Gazit, E.,Motta, A.; Converting the highly amyloidogenic human calcitonin into a powerful fibril inhibitor by 3D structure homology with a non-amyloidogenic analogue; J.Biol.Chem., 286:2707-2718, 2011; PubMed: 21078667; DOI: 10.1074/jbc.M110.182014

実験手法

SOLUTION NMR