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2JWA

ErbB2 transmembrane segment dimer spatial structure

Summary for 2JWA
Entry DOI10.2210/pdb2jwa/pdb
DescriptorReceptor tyrosine-protein kinase erbB-2 (1 entity in total)
Functional Keywordstransmembrane helix dimer, erbb2, protein kinase receptor membrane domain, atp-binding, glycoprotein, nucleotide-binding, phosphorylation, polymorphism, transferase, tyrosine-protein kinase
Biological sourceHomo sapiens (human)
Cellular locationIsoform 1: Cell membrane; Single-pass type I membrane protein. Isoform 2: Cytoplasm. Isoform 3: Cytoplasm: P04626
Total number of polymer chains2
Total formula weight9469.61
Authors
Mineev, K.S.,Bocharov, E.V.,Arseniev, A.S. (deposition date: 2007-10-09, release date: 2008-01-22, Last modification date: 2022-03-16)
Primary citationBocharov, E.V.,Mineev, K.S.,Volynsky, P.E.,Ermolyuk, Y.S.,Tkach, E.N.,Sobol, A.G.,Chupin, V.V.,Kirpichnikov, M.P.,Efremov, R.G.,Arseniev, A.S.
Spatial Structure of the Dimeric Transmembrane Domain of the Growth Factor Receptor ErbB2 Presumably Corresponding to the Receptor Active State
J.Biol.Chem., 283:6950-6956, 2008
Cited by
PubMed: 18178548
DOI: 10.1074/jbc.M709202200
PDB entries with the same primary citation
Experimental method
SOLUTION NMR
Structure validation

217705

건을2024-03-27부터공개중

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