2JT6
Solution structure of matrix metalloproteinase 3 (MMP-3) in the presence of 3-4'-cyanobyphenyl-4-yloxy)-n-hdydroxypropionamide (MMP-3 inhibitor VII)
Summary for 2JT6
| Entry DOI | 10.2210/pdb2jt6/pdb |
| Related | 2JNP 2JT5 |
| NMR Information | BMRB: 15396 |
| Descriptor | Stromelysin-1, ZINC ION, CALCIUM ION, ... (4 entities in total) |
| Functional Keywords | metalloproteinase, mmp, calcium, collagen degradation, extracellular matrix, glycoprotein, hydrolase, metal-binding, metalloprotease, polymorphism, protease, zinc, zymogen |
| Biological source | Homo sapiens (human) |
| Total number of polymer chains | 1 |
| Total formula weight | 18536.31 |
| Authors | Alcaraz, L.A.,Banci, L.,Bertini, I.,Cantini, F.,Donaire, A.,Gonnelli, L. (deposition date: 2007-07-23, release date: 2008-02-19, Last modification date: 2020-02-19) |
| Primary citation | Alcaraz, L.A.,Banci, L.,Bertini, I.,Cantini, F.,Donaire, A.,Gonnelli, L. Matrix metalloproteinase-inhibitor interaction: the solution structure of the catalytic domain of human matrix metalloproteinase-3 with different inhibitors J.Biol.Inorg.Chem., 12:1197-1206, 2007 Cited by PubMed: 17710450DOI: 10.1007/s00775-007-0288-9 PDB entries with the same primary citation |
| Experimental method | SOLUTION NMR |
Structure validation
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