2JT6

Solution structure of matrix metalloproteinase 3 (MMP-3) in the presence of 3-4'-cyanobyphenyl-4-yloxy)-n-hdydroxypropionamide (MMP-3 inhibitor VII)

2JT6 の概要

• エントリーDOI: 10.2210/pdb2jt6/pdb
• 関連するPDBエントリー: 2JNP 2JT5
• NMR情報: BMRB: 15396
• 分子名称: Stromelysin-1, ZINC ION, CALCIUM ION, ... (4 entities in total)
• 機能のキーワード: metalloproteinase, mmp, calcium, collagen degradation, extracellular matrix, glycoprotein, hydrolase, metal-binding, metalloprotease, polymorphism, protease, zinc, zymogen
• 由来する生物種: Homo sapiens (human)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 18536.31

構造登録者

Alcaraz, L.A.,Banci, L.,Bertini, I.,Cantini, F.,Donaire, A.,Gonnelli, L. (登録日: 2007-07-23, 公開日: 2008-02-19, 最終更新日: 2020-02-19)

• 主引用文献: Alcaraz, L.A.,Banci, L.,Bertini, I.,Cantini, F.,Donaire, A.,Gonnelli, L.; Matrix metalloproteinase-inhibitor interaction: the solution structure of the catalytic domain of human matrix metalloproteinase-3 with different inhibitors; J.Biol.Inorg.Chem., 12:1197-1206, 2007; PubMed: 17710450; DOI: 10.1007/s00775-007-0288-9

実験手法

SOLUTION NMR