2JOK

NMR structure of the catalytic domain of guanine nucleotide exchange factor BopE from Burkholderia pseudomallei

2JOK の概要

• エントリーDOI: 10.2210/pdb2jok/pdb
• 関連するPDBエントリー: 1GZS 1R6E 1R9K 2JOL
• 分子名称: Putative G-nucleotide exchange factor (1 entity in total)
• 機能のキーワード: guanine nucleotide exchange factor, burkholderia pseudomallei, type iii secretion, sope, sope2, cell invasion, signaling protein
• 由来する生物種: Burkholderia pseudomallei
• 細胞内の位置: Secreted: Q63K41
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 20136.34

構造登録者

Wu, H.,Upadhyay, A.,Williams, C.,Galyov, E.E.,van den Elsen, J.M.H.,Bagby, S. (登録日: 2007-03-14, 公開日: 2007-09-18, 最終更新日: 2023-12-20)

• 主引用文献: Upadhyay, A.,Wu, H.L.,Williams, C.,Field, T.,Galyov, E.E.,van den Elsen, J.M.,Bagby, S.; The guanine-nucleotide-exchange factor BopE from Burkholderia pseudomallei adopts a compact version of the Salmonella SopE/SopE2 fold and undergoes a closed-to-open conformational change upon interaction with Cdc42; Biochem.J., 411:485-493, 2008; PubMed: 18052936; DOI: 10.1042/BJ20071546

実験手法

SOLUTION NMR