2JO9

Mouse Itch 3rd WW domain complex with the Epstein-Barr virus latent membrane protein 2A derived peptide EEPPPPYED

2JO9 の概要

• エントリーDOI: 10.2210/pdb2jo9/pdb
• 関連するPDBエントリー: 2JOC
• NMR情報: BMRB: 15153
• 分子名称: Itchy E3 ubiquitin protein ligase, Latent membrane protein 2 (2 entities in total)
• 機能のキーワード: itch, ww, complex, epstein-barr virus, lmp2a, ligase
• 由来する生物種: Mus musculus (house mouse); 詳細
• 細胞内の位置: Cell membrane (By similarity): Q8C863; Isoform LMP2A: Host cell membrane; Multi- pass membrane protein. Isoform LMP2B: Host endomembrane system; Multi-pass membrane protein: P13285
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 5348.79

構造登録者

Macias, M.J.,Shaw, A.Z.,Martin-Malpartida, P.,Morales, B.,Ruiz, L.,Ramirez-Espain, X.,Yraola, F.,Royo, M. (登録日: 2007-03-01, 公開日: 2007-04-17, 最終更新日: 2023-12-20)

• 主引用文献: Morales, B.,Ramirez-Espain, X.,Shaw, A.Z.,Martin-Malpartida, P.,Yraola, F.,Sanchez-Tillo, E.,Farrera, C.,Celada, A.,Royo, M.,Macias, M.J.; NMR Structural Studies of the ItchWW3 Domain Reveal that Phosphorylation at T30 Inhibits the Interaction with PPxY-Containing Ligands; Structure, 15:473-483, 2007; PubMed: 17437719; DOI: 10.1016/j.str.2007.03.005

実験手法

SOLUTION NMR